Manufacturer Good Price N,N-DIMETHYLFORMAMIDE(DMF) CAS 68-12-2
description
The name comes from the fact that it is the dimethyl substitution of formamide (amide of formic acid), and both methyl groups are located on the N (nitrogen) atom. N,N-DIMETHYLFORMAMID is a high-boiling polar (hydrophilic) aprotic solvent, and Chemicalbook can promote the SN2 reaction mechanism. N,N-DIMETHYLFORMAMID is produced using formic acid and dimethylamine. N,N-DIMETHYLFORMAMID is unstable (especially at high temperature) in the presence of strong bases such as sodium hydroxide or strong acids such as hydrochloric acid or sulfuric acid, and hydrolyzes to formic acid and dimethylamine. It is very stable in air and when heated to boiling. When the temperature is higher than 350 ℃, it will lose water and generate carbon monoxide and dimethylamine. N,N-DIMETHYLFORMAMID is a good aprotic polar solvent, which can dissolve most organic and inorganic substances, and is miscible with water, alcohols, ethers, aldehydes, ketones, esters, halogenated hydrocarbons and aromatic hydrocarbons, etc. . The positively charged end of the N,N-DIMETHYLFORMAMID molecule is surrounded by methyl groups, forming a steric hindrance, so that negative ions cannot approach, but only positive ions are associated. The naked anion is much more active than the solvated anion. Many ionic reactions are more easily carried out in N,N-DIMETHYLFORMAMID than in general protic solvents, for example, the reaction of carboxylates with halogenated hydrocarbons in N,N-DIMETHYLFORMAMID at room temperature , can generate high-yield esters, especially suitable for the synthesis of sterically hindered esters.
Synthesis.Synonyms
amide,n,n-dimethyl-formicaci; Dimethylamidkyselinymravenci; dimethylamidkyselinymravenci; N,N-DIMETHYLFORMAMIDE,99.9+%,HPLCGRADE; NN-DIMETHYLFORChemicalbookMAMIDE99.8%A.C.S.&; N,N-DIMETHYLFORMAMIDE,4X25ML; N,N-DIMETHYLFORMAMIDE,MOLECULARBIOLOGYREAGENT; N,N-DIMETHYLFORMAMIDENEUTRALMARKER*FORCAPILLARY
Applications of DMF
DMF is a good solvent for a variety of high polymers such as polyethylene, polyvinyl chloride, polyacrylonitrile, polyamide, etc., and can be used for wet spinning of synthetic fibers such as polyacrylonitrile fibers, and synthesis of polyurethane; It is used for plastic film making; it can also be used as a paint stripper for removing paint; it can also dissolve some low-solubility pigments, so that the pigments have the characteristics of dyes. DMF is used for aromatic extraction and separation and recovery of butadiene from C4 fractions and isoprene from C5 fractions, and can also be used as an effective reagent for the separation of non-hydrocarbon components from paraffin . It has good selectivity for the solubility of isophthalic acid and terephthalic acid: isophthalic acid is more soluble in DMF than terephthalic acid, solvent extraction or partial Crystallization, the two can be separated. In the petrochemical industry, DMF can be used as a gas absorbent to separate and refine gases. As a curing agent for washing Chemicalbook in the polyurethane industry, it is mainly used in the production of wet synthetic leather; as a solvent in the acrylic fiber industry, it is mainly used in the dry spinning production of acrylic fiber; in the electronic industry as a quenching of tin-plated parts and circuit boards Other industries include carriers of dangerous gases, solvents for drug crystallization, adhesives, etc. In organic reactions, DMF is not only widely used as a solvent for the reaction, but also an important intermediate in organic synthesis. In the pesticide industry, it can be used to produce ciprofloxacin; in the pharmaceutical industry, it can be used to synthesize iodine, doxycycline, cortisone, vitamin B6, iodine, quercetin, pyrantel, N-formylsarcomin, Oncoline, methoxyfen, benzodiazepine, cyclohexyl nitrosourea, furoflurouracil, hemostatic acid, bepartame, megestrol, bilevita, chlorpheniramine, sulfonamides Production. DMF has a catalytic effect in the reactions of hydrogenation, dehydrogenation, dehydration and dehydrohalogenation, so that the reaction temperature is lowered and the product purity is improved.
1. It is an excellent organic solvent, used as a solvent for polyurethane, polyacrylonitrile, and polyvinyl chloride, and also used as an extractant, as a raw material for medicines and pesticides.
2. Used as analytical reagent and solvent for vinyl resin and acetylene
3. It is not only a chemical raw material with a wide range of uses, but also an excellent solvent with a wide range of uses. DMF is a good solvent for a variety of high polymers such as polyethylene, polyvinyl chloride, polyacrylonitrile, polyamide, etc., and can be used for wet spinning of synthetic fibers such as polyacrylonitrile fibers, and synthesis of polyurethane; It is used for plastic film making; it can also be used as a paint stripper for removing paint; it can also dissolve some low-solubility pigments, so that the pigments have the characteristics of dyes. DMF is used for aromatic extraction and separation and recovery of butadiene from C4 fractions and isoprene from C5 fractions, and can also be used as an effective reagent for the separation of non-hydrocarbon components from paraffin . It has good selectivity for the solubility of isophthalic acid and terephthalic acid: isophthalic acid is more soluble in DMF than terephthalic acid, solvent extraction is carried out in dimethyl chemicalbook acid formamide Or partially crystallized, the two can be separated. In the petrochemical industry, DMF can be used as a gas absorbent to separate and refine gases. In organic reactions, DMF is not only widely used as a solvent for the reaction, but also an important intermediate in organic synthesis. In the pesticide industry, it can be used to produce ciprofloxacin; in the pharmaceutical industry, it can be used to synthesize iodine, doxycycline, cortisone, vitamin B6, iodine, quercetin, pyrantel, N-formylsarcomin, Tumorine, Methoxyfen mustard, Bian nitrogen mustard, cyclohexyl nitrosourea, furoflurouracil, hemostatic acid, bepartame, megestrol, bilevitamin, chlorpheniramine, etc. DMF has a catalytic effect in the reactions of hydrogenation, dehydrogenation, dehydration and dehydrohalogenation, so that the reaction temperature is lowered and the product purity is improved.
4. Non-aqueous titration solvent. Solvent for vinyl and acetylene. Photometric determination. Gas chromatographic stationary solution (maximum operating temperature 50 ℃, solvent is methanol), separation Chemicalbook analysis C2 ~ C5 hydrocarbons, and can separate normal, isobutene and cis, trans-2-butene. Pesticide residue analysis. Organic Synthesis. Peptide synthesis. For the photographic industry.
Specification of DMF
|
Compound |
Specification |
|
Appearance |
clear |
|
General |
≥99.9% |
|
Methanol |
≤0.001% |
|
Color (PT-CO),Hazen |
≤5 |
|
Water,% |
≤0.05% |
|
Iron, mg/kg |
≤0.05 |
|
Acidity(HCOOH) |
≤0.001% |
|
Basicity (DMA) |
≤0.001% |
|
PH(25℃, 20% aqueous) |
6.5-8.0 |
|
Conductivity(25℃, 20% aqueous),μs/cm |
≤2 |
Packing of DMF
190kg/drum
Storage should be at cool, dry and ventilate.
